Microfluidic proximal tubule kidney-on-chip
US11841361B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Aug 19, 2021 |
| Grant date | Dec 12, 2023 |
| Priority date | — |
| Expiry date | Dec 2, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/90
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to microfluidic fluidic devices, methods and systems as microfluidic kidney on-chips, e.g. human Proximal Tubule-Kidney-Chip, Glomerulus (Kidney)-Chip, Collecting Duct (Kidney)-Chip. Devices, methods and systems are described for drug testing including drug transport and renal clearance. Further, such devices, methods and systems are used for determining drug-drug interactions and their effect upon renal transporter functions. Importantly, they may be used for pre-clinical and clinical drug development for treating kidney diseases and for personalized medicine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.