Fusion protein comprising glutathione-s-transferase and protein having binding affinity target cell or target protein, and use thereof

US11844844B2 · kind B2 · utility

Assignee

• UNIST(ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) · KR

Inventors

• Ja Hyoung Ryu · Ulsan, KR
• Joon Yong Oh · Ulsan, KR
• Han Sol Kim · Daejeon, KR
• Chae Kyu Kim · Daejeon, KR
• Se Byung Kang · Ulsan, KR

Key dates

• Filing date: Nov 28, 2018
• Grant date: Dec 19, 2023
• Expiry date: May 6, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/74
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are a fusion protein including glutathione-S-transferase and a protein having binding affinity for a target cell or a target protein, and use thereof as a drug delivery carrier and a pharmaceutical composition. The fusion protein and the drug delivery carrier including the same according to an aspect may sustain an in vivo residence time, and may also have improved target cell-targeting ability, and thus may be effectively delivered to target cells. Accordingly, it may be usefully applied to a targeted therapeutic agent.