Recombinant human collagen-based multifunctional stent coating and preparation method thereof
US11844880B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 26, 2021 |
| Grant date | Dec 19, 2023 |
| Priority date | — |
| Expiry date | Jul 3, 2041 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB05D2202/00
- WIPO fieldSurface technology, coating
- WIPO sectorChemistry
Abstract
A recombinant human collagen-based multifunctional stent coating and a preparation method thereof are provided. The preparation method includes (1) activating a substrate material; (2) placing the activated substrate material in an amino compound-containing solution for a reaction to obtain an aminated substrate material; (3) placing the aminated substrate material in a polyanion electrolyte solution for a reaction, and cleaning with deionized water. The recombinant human collagen-based multifunctional stent coating prepared by the present invention effectively improves the anticoagulation and rapid endothelialization performance of biomaterials, such as vascular stent materials, and reduces the late thrombosis and restenosis problems existing in current stent materials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.