PRMT5 inhibitors
US11845760B2 · kind B2 · utility
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46Claims
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Assignee
Inventors
Key dates
| Filing date | Dec 15, 2021 |
| Grant date | Dec 19, 2023 |
| Priority date | — |
| Expiry date | Jan 14, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Described herein are novel PRMT5 inhibitors of Formula I and pharmaceutically acceptable salts thereof, as well as the pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity and may have use in treating proliferative, metabolic and blood disorders. Compounds of Formula I have the following structure:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.