Anti-TCR antibody molecules and uses thereof

US11845797B2 · kind B2 · utility

Assignee

• MARENGO THERAPEUTICS, INC. · US

Inventors

• Seng-Lai Tan · Sudbury, US
• Brian Edward Vash · Cambridge, US
• Jonathan Hsu · Cambridge, US
• Dilini Charmain Gunasekera · Cambridge, US
• Sangeetha Sagar Palakurthi · East Walpole, US
• Andreas Loew · Somerville, US

Key dates

• Filing date: Jul 3, 2019
• Grant date: Dec 19, 2023
• Expiry date: Jun 27, 2040

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure provides antibody molecules that bind to TCR Vβ regions and multispecific molecules comprising said antibody molecules. Additionally, disclosed are nucleic acids encoding the same, methods of producing the aforesaid molecules, pharmaceutical compositions comprising aforesaid molecules, and methods of treating a cancer using the aforesaid molecules.