Compositions and methods for genome editing
US11845942B2 · kind B2 · utility
1Cited by
15References
19Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 7, 2018 |
| Grant date | Dec 19, 2023 |
| Priority date | — |
| Expiry date | Jun 7, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/20
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides compositions, methods, and systems for targeted plant genome editing. In some embodiments, the present disclosure provides recombinant self-replicating RNAs derived from a plant virus vector, such as those derived from Tobacco Mosaic Virus (TMV). In some embodiments, the recombinant self-replicating RNAs direct the expression of both a CRISPR endonuclease and a guide RNA capable of directing sequence-specific binding of the CRISPR endonuclease to a target DNA in the genome of plant cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.