Patent · US Active

Muconic acid-producing transformed microorganism and use thereof

US11845972B2 · kind B2 · utility

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Key dates

Filing dateOct 17, 2019
Grant dateDec 19, 2023
Priority date
Expiry dateJun 14, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y401/01063
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The objective of the present invention is to provide a microorganism that makes it possible to produce muconic acid from a lignin-derived aromatic compound with sufficient economic efficiency and without depending on the type of lignin, and a method of producing muconic acid using the microorganism. The objective can be achieved by a transformed microorganism wherein the host microorganism is a microorganism of the genus Pseudomonas that has pcaH gene, pcaG gene, catA gene, and catB gene on its chromosome, and that can assimilate an aromatic compound derived from syringyl lignin; and wherein the transformed microorganism lacks at least one gene selected from the group consisting of pcaH gene and pcaG gene on its chromosome, lacks catB gene on its chromosome, and expresses aroY gene inserted; and a method of producing muconic acid using the transformed microorganism and the like.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.