Patent · US Active

Normalization of nucleic acid libraries

US11845986B2 · kind B2 · utility

0Cited by

188References

15Claims

0Family size

Assignee

Becton, Dickinson and Company · US

Inventors

Eleen Shum · San Jose, US
Glenn K. Fu · Dublin, US
Craig Betts · Menlo Park, US

Key dates

Filing date	Apr 3, 2019
Grant date	Dec 19, 2023
Priority date	—
Expiry date	Apr 3, 2039

Classification

Technology area (CPC G)Physics
CPC primaryG16B25/10
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

This disclosure provides methods and compositions for removing one or more high abundance species from a plurality of nucleic acid molecules. In some embodiments, the methods and compositions can be used for normalizing nucleic acid libraries. In some embodiments, molecular labels are used in conjunction with the methods and compositions disclosed herein to improve sequencing efficiency.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.