Interleukin-18 variants and methods of use
US11850276B2 · kind B2 · utility
2Cited by
1References
31Claims
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Key dates
| Filing date | Dec 1, 2022 |
| Grant date | Dec 26, 2023 |
| Priority date | — |
| Expiry date | Dec 1, 2042 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides compositions and methods comprising stabilized IL-18 polypeptides for use in therapeutic and non-therapeutic applications. In some cases, the stabilized IL-18 proteins provide IL-18 signaling activity even in the presence of an inhibitory molecule such as IL-18BP. Also provide are methods of administration and methods for making active polypeptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.