CAR T-cells comprising transcriptional circuits
US11851672B2 · kind B2 · utility
1Cited by
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2Claims
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Key dates
| Filing date | Oct 24, 2018 |
| Grant date | Dec 26, 2023 |
| Priority date | — |
| Expiry date | Sep 5, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a kit of vectors for transducing an immune cell with multiple transgenes comprising: (i) a first vector which comprises a first transgene and a nucleotide sequence encoding a transcription factor and; and (ii) a second vector which comprises a second transgene wherein expression of the second transgene within a host cell is dependent upon expression of the transcription factor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.