Methods and devices for the generation of oocytes with improved oocyte quality for in vitro fertilization procedures using non-invasive cellular transfer
US11851675B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jan 26, 2021 |
| Grant date | Dec 26, 2023 |
| Priority date | — |
| Expiry date | Mar 11, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/1382
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The subject invention pertains to methods and devices for generating mature oocytes from immature oocytes and improving oocyte quality for improved success of assistant reproductive technology (ART). The methods include the use of tunneling nanotube-forming cells and oocytes, wherein the tunneling nanotube-forming cells transfer autologous genomic materials, biomolecules and cellular components to the oocytes. The devices of the invention include microfluidic device to improve the efficiency of the transfer of biomolecules and cellular components between tunneling nanotube-forming cells and oocytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.