Patent · US Active

Method for preparing an antimycin compound produced by Streptomyces sp.4-7

US11851692B2 · kind B2 · utility

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Assignee

Ningbo University · CN

Inventors

Lijian Ding · Beijing, CN
Shan He · College Park, US
Wenhao Li · South San Francisco, US
Weiyan ZHANG · Ningbo City, CN
Yingying Wei · Ningbo City, CN

Key dates

Filing date	Mar 29, 2023
Grant date	Dec 26, 2023
Priority date	—
Expiry date	Mar 29, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D321/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed are an antimycin compound and a preparation method and use thereof. The preparation method comprises: fermenting a marine actinomycete (Streptomyces sp.4-7) with a preservation number CCTCCNO: M2020953 to obtain a fermented product and soaking and extracting the fermented product with ethyl acetate to obtain a crude extract; and carrying out separation and purification by normal-phase silica gel column chromatography, reversed-phase MPLC, and semi-preparative reversed-phase high-performance liquid chromatography. The invention has the advantages of resistance against Botrytis cinerea and Penicillium citrinum.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.