Method and device for superresolution optical measurement using singular optics
US11852459B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 6, 2023 |
| Grant date | Dec 26, 2023 |
| Priority date | — |
| Expiry date | Mar 6, 2043 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/12
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for measuring a position of a fluorophore includes configuring a set of compact light distributions, the set having at least one member, each light distribution characterized by a center, so that there is substantially zero intensity at the center of the set of compact light distributions. The method additionally includes moving the set of compact light distributions in relation to a set of hypothesized positions of the fluorophore, detecting, in a plurality of locations corresponding to the hypothesized set of positions, a set of images; and estimating the position of the fluorophore, by determining from the set of images a set of parameters describing the position of the fluorophore using an inverse problem method.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.