Metal-organic frameworks for electrochemical detection of analytes

US11852605B2 · kind B2 · utility

Assignee

• TRUSTEES OF DARTMOUTH COLLEGE · US

Inventors

• Katherine A. Mirica · Hanover, US
• Lukasz K. Mendecki · White River Junction, US
• Michael Y. Ko · Lebanon, US
• Zheng Meng · 安丰镇, CN
• Robert Stolz · Schweinfurt, DE
• Aileen Eagleton · Hanover, US

Key dates

• Filing date: Jun 21, 2019
• Grant date: Dec 26, 2023
• Expiry date: Feb 29, 2040

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/575
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

In some embodiments, the present disclosure pertains to methods of detecting an analyte in a sample by associating the sample with an electrode that includes a metal-organic framework. After association, the redox properties of the electrode are evaluated. Thereafter, the presence or absence of the analyte in the sample is detected by correlating the redox properties of the electrode to the presence or absence of the analyte. In some embodiments, the present disclosure pertains to electrodes that include a metal-organic framework and an electrode surface. In particular embodiments of the present disclosure, the metal-organic framework is associated with the electrode surface. Additional embodiments of the present disclosure pertain to methods of making the electrodes of the present disclosure by associating a metal-organic framework with an electrode surface. In some embodiments, the methods of the present disclosure also include a step of mixing the metal-organic framework with a polymer.