Pyrimidine small-molecule compound and application thereof
US11858914B2 · kind B2 · utility
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Key dates
| Filing date | Jun 8, 2023 |
| Grant date | Jan 2, 2024 |
| Priority date | — |
| Expiry date | Jun 8, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are a pyrimidine small-molecule compound and an application thereof. The pyrimidine small-molecule compound has efficient inhibitory activity towards PDGFRα and PDGFRβ kinases, but has relatively weak inhibitory activity towards other kinases. Therefore, the compound has very high selectivity and is capable of being used as a potential drug for resisting tumors or relieving ophthalmic diseases such as wet age-related macular degeneration or uveitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.