Human PD-L1-binding immunoglobulins

US11858960B2 · kind B2 · utility

Assignee

• VRIJE UNIVERSITEIT BRUSSEL · BE

Inventors

• Jo Van Ginderachter · Ninove, BE
• Geert Raes · Sint-Genesius-Rode, BE
• Nick Devoogdt · Zemst, BE
• Marleen Keyaerts · Tervuren, BE
• Quentin Lecocq · Ganshoren, BE
• Catarina Xavier · Merchtem, BE
• Karine Breckpot · Brussels, BE
• Katrijn Broos · Sint-Katelijne-Waver, BE
• Jessica Bridoux · Etterbeek, BE

Key dates

• Filing date: Mar 1, 2019
• Grant date: Jan 2, 2024
• Expiry date: Mar 24, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/21
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to polypeptides, in particular polypeptides comprising an immunoglobulin domain, binding to human Programmed Death Ligand-1 (huPDL1) and to applications of such polypeptides such as for use as a medicament or for use as diagnostic agent, for example as an immunotracer.