Fibronectin based scaffold domain proteins that bind PCSK9
US11858979B2 · kind B2 · utility
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28References
10Claims
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Key dates
| Filing date | Feb 16, 2021 |
| Grant date | Jan 2, 2024 |
| Priority date | — |
| Expiry date | Jul 5, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to fibronectin based scaffold domain proteins that bind PCSK9. The invention also relates to the use of the innovative proteins in therapeutic applications to treat atherosclerosis, hypercholesterolemia and other cholesterol related diseases. The invention further relates to cells comprising such proteins, polynucleotides encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.