Patent · US Active

Recombinant bacteria engineered to treat diseases associated with methionine metabolism and methods of use thereof

US11859189B2 · kind B2 · utility

0Cited by

0References

14Claims

0Family size

Assignees

Synlogic Operating Company, Inc. · US
Ginkgo Bioworks, Inc. · US

Inventors

Dylan Alexander Carlin · Brookline, US
Vincent M. Isabella · Medford, US
Jonathan McMurry · Marietta, US
Theodore Carlton Moore, III · Cambridge, US
Mylene Perreault · Lexington, US
Nathan W. Schmidt · Milton, US
Mark David Simon · Somerville, US

Key dates

Filing date	Aug 11, 2022
Grant date	Jan 2, 2024
Priority date	—
Expiry date	Aug 11, 2042

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present disclosure provides host cells, e.g., bacterial cells, that comprise a methionine decarboxylase enzyme for the treatment of diseases and disorders associated with methionine metabolism in a subject. The disclosure further provides pharmaceutical compositions and methods of treating disorders associated with methionine metabolism, such as homocystinuria.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.