Methods of producing epimerases and benzylisoquinoline alkaloids
US11859225B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | May 9, 2016 |
| Grant date | Jan 2, 2024 |
| Priority date | — |
| Expiry date | May 9, 2036 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/22
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of epimerizing an (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid is provided. The method comprises contacting the (S)-1-benzylisoquinoline alkaloid with at least one enzyme. Contacting the (S)-1-benzylisoquinoline alkaloid with the at least one enzyme converts the (S)-1-benzylisoquinoline alkaloid to an (R)-1-benzylisoquinoline alkaloid.
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