Antiviral drugs targeting the N-terminal domain (NTD) of the coronavirus spike receptor binding domain (RBD)

US11865111B2 · kind B2 · utility

Assignees

• SOUTHWEST RESEARCH INSTITUTE · US
• The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. · US
• The Government of the United States, as represented by the Secretary of the Army · US

Inventors

• Jonathan A. BOHMANN · San Antonio, US
• Nadean M. Gutierrez · Devine, US
• Joseph A. McDonough · Port Aransas, US
• Robert Campbell · Niskayuna, US
• Michael Gordon Joyce · Washington, US
• Rekha Panchal · Des Moines, US
• Rajeshwer Sankhala · Bethesda, US
• Allen J. Duplantier · Ledyard, US

Key dates

• Filing date: Aug 11, 2022
• Grant date: Jan 9, 2024
• Expiry date: Aug 11, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D409/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Antiviral drugs targeting the N-terminal domain (NTD) of the spike receptor binding domain (RBD) and methods of treating a subject suffering from coronavirus.