Splice-switching oligonucleotides and methods of use
US11866689B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Mar 22, 2019 |
| Grant date | Jan 9, 2024 |
| Priority date | — |
| Expiry date | Mar 22, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR expression and methods of using these splice-switching oligonucleotides to treat cancer, specifically castrate resistant prostate cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.