Method and system for dissociating biological tissue into single cells using ultrasonic energy
US11866694B2 · kind B2 · utility
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29Claims
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Key dates
| Filing date | Oct 1, 2020 |
| Grant date | Jan 9, 2024 |
| Priority date | — |
| Expiry date | Dec 4, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2523/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method of dissociating single cells from a biological tissue sample is described herein, along with systems for performing such methods. The method includes generating one or more ultrasonic wave pulses using a transducer comprising one or more Fresnel Annular Sector Actuator (FASA) elements; and applying energy from the generated one or more ultrasonic wave pulses to a sample container holding the biological tissue sample through a coupling medium that couples the one or more FASA elements to the sample container to dissociate single cells from the biological tissue is described herein.
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