Indanes as PD-L1 inhibitors

US11872217B2 · kind B2 · utility

Assignee

• CHEMOCENTRYX, INC. · US

Inventors

• Viengkham Malathong · Mountain View, US
• Venkat Reddy Mali · Cupertino, US
• Darren McMurtrie · Daly City, US
• Sreenivas Punna · Sunnyvale, US
• Howard S. Roth · Champaign, US
• Rajinder Singh · Belmont, US
• Ju Yang · Palo Alto, US
• Penglie Zhang · Foster City, US

Key dates

• Filing date: Jul 9, 2020
• Grant date: Jan 16, 2024
• Expiry date: Aug 11, 2040

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds represented by Formula (I) or (II): are provided herein, or a pharmaceutically acceptable salt, or a prodrug or bioisostere thereof; wherein R1, R2a, R2b, R2c, R3, R4, R5, R6a, R6b, R2a′, R2b′, R2c′, R3′, R4′, R5′, R6a′, R6b′, Y, Y′, and the subscripts m and n are as defined herein.