Patent · US Active

Pyruvate kinase modulators and use thereof

US11872225B2 · kind B2 · utility

0Cited by

5References

22Claims

0Family size

Assignee

Agios Pharmaceuticals, Inc. · US

Inventors

Giovanni Cianchetta · Waltham, US
Charles Kung · Arlington, US
Tao Liu · Shanghai, CN
Anil Kumar Padyana · Oxford, US
Zhihua Sui · Flemington, US
Zhenwei Cai · Skillman, US
Dawei Cui · Shanghai, CN
Jingjing Ji · Shanghai, CN

Key dates

Filing date	Jan 27, 2022
Grant date	Jan 16, 2024
Priority date	—
Expiry date	Jan 27, 2042

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K45/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Described herein are methods of using compounds of Formula (I) to modulate PKM2 activity in a subject. These compounds are represented by Formula (I): wherein R1, R2, L1, and L2 are as defined herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.