Patent · US Active

Transcriptome in vivo analysis (TIVA) and transcriptome in situ analysis (TISA)

US11873312B2 · kind B2 · utility

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5References
9Claims
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Assignee

Inventors

Key dates

Filing dateMay 28, 2021
Grant dateJan 16, 2024
Priority date
Expiry dateFeb 1, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2310/531
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Compositions and methods of capturing one or more nucleic acid molecules of a cell or subcellular compartment are described. In certain aspects, the compositions comprise a caged molecule comprising one or more photolinkers and an antisense oligonucleotide, which when uncaged hybridizes to a target nucleic acid molecule.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.