Sequencing methods using improved nucleotide reagent solutions
US11873526B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Jan 7, 2022 |
| Grant date | Jan 16, 2024 |
| Priority date | — |
| Expiry date | Mar 1, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A reagent solution includes water, a nucleotide, and tris(2-carboxyethyl)phosphine in a range of 0.5 μM to 1000 μM. The reagent solution can further include a non-ionic surfactant in an amount of 0.001% to 1% or a biocidal agent in an amount of 0.001% to 1%. The reagent solution can include salts, such as sodium chloride or magnesium sulfate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.