Photoelectrochemical biosensor and methods of use thereof
US11874247B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 3, 2021 |
| Grant date | Jan 16, 2024 |
| Priority date | — |
| Expiry date | Sep 3, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/3276
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided herein is a biosensor for detecting a target analyte in a sample comprising a first and second photoelectrode each comprising conductive substrate and photoactive material, a first and second capture probe functionalized on the first and second photoelectrode, respectively, and optionally one or more reporter moieties comprising a detectable label, wherein the first and second capture probe each, independently, provides a distance between the detectable label and the photoactive material in the presence of the target analyte, wherein intensity of detection signal dictated by the distance is generated from the first and second photoelectrode by transfer of electrons between the detectable label and the photoactive material, wherein a higher, or higher increase than in absence of sample, in the intensity of the detection signal from the first as compared to the second photoelectrode in the presence of the sample, is indicative of the presence of the target analyte.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.