Substituted 4-benzyl and 4-benzoyl piperidine derivates
US11878966B2 · kind B2 · utility
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1Claims
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Key dates
| Filing date | Feb 15, 2021 |
| Grant date | Jan 23, 2024 |
| Priority date | — |
| Expiry date | May 14, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Described herein are 1,4-substituted piperidine compounds according to Formula I that have demonstrated activity as fatty acid synthase inhibitors. Also described herein are pharmaceutical compositions containing the described 1,4-substituted piperidine compounds. Also described herein are methods of treating diseases mediated by fatty acid synthase, by administering one or more of the compounds or pharmaceutical formulations described herein. Also described herein are methods of synthesizing the described 1,4-substituted piperidine compounds and synthetic intermediates useful in those syntheses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.