Patent · US Active

Aryl compounds and pharmaceutical compositions that modulate IKZF2

US11878968B2 · kind B2 · utility

0Cited by
2References
40Claims
0Family size

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Key dates

Filing dateNov 3, 2022
Grant dateJan 23, 2024
Priority date—
Expiry dateNov 3, 2042

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/84
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Disclosed are compounds and salts thereof that bind to and modulate cereblon activity. In some embodiments, the binding and modulation of cereblon results in the degradation of IKAROS family zinc finger proteins (e.g., IKZF2). The compounds are of formula I:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.