Patent · US Active

GalNAc compositions for improving siRNA bioavailability

US11879125B2 · kind B2 · utility

2Cited by

87References

20Claims

0Family size

Assignee

EMPIRICO INC. · US

Inventors

Darren H. Wakefield · Fitchburg, US
David B. Rozema · Madison, US
Omri GOTTESMAN · Sierra Sky Park, US

Key dates

Filing date	Mar 15, 2023
Grant date	Jan 23, 2024
Priority date	—
Expiry date	Mar 15, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2320/32
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided herein, are compositions comprising GaINAc moieties that may be conjugated to an oligonucleotide. The oligonucleotide may be a small interfering RNA or an antisense oligonucleotide. Also provided herein are methods of treatment that include administering the composition to a subject.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.