System, apparatus and method for sensing, detecting and effecting in a micro-to-nano environment
US11879892B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 6, 2020 |
| Grant date | Jan 23, 2024 |
| Priority date | — |
| Expiry date | May 19, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/325
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus that is μm- or nm-scale in size and can include integrated circuitry logic based on sub 10 nm SIA transistor nodes, a sensing subsystem, a deciding subsystem, an effecting subsystem, and a power harvesting system is described. The sensing subsystem can identify pathogenic entities, including disease associated cells (for example, cancer cells, autoimmune cells, or pathological microbes) or viruses. The sensing subsystem can include at least one pad constructed of an electrically conductive material and linkers attached to the at least one pad. Each linker can also be attached to a targeting agent (for example, an antibody fragment) or a reference agent. Upon the binding of a targeting agent with an entity of interest, the information is transferred to the logic circuitry, which processes the binding event information and decides whether the entity is disease associated (e.g., a disease associated cell or virus) and requires delivery of therapeutic agents or other treatment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.