Composition for skin whitening comprising β-mangostin as effective ingredient
US11882858B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 20, 2016 |
| Grant date | Jan 30, 2024 |
| Priority date | — |
| Expiry date | Jun 12, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/805
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A skin whitening composition includes β-mangostin or a cosmetically acceptable salt thereof as an effective ingredient. β-Mangostin represented by Chemical Formula 1 suppresses the expression of tyrosinase and TRP-1 (tyrosinase-related protein-1) and induces autophagy of a melasosome. As such, it was confirmed that the β-mangostin not only suppresses melanin production but also exhibits the effect of removing previously formed melanin. Accordingly, the β-mangostin can be advantageously used as a functional material for skin whitening and skin lightening.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.