Antibody variable domains targeting the NKG2D receptor
US11884733B2 · kind B2 · utility
6Cited by
60References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 2019 |
| Grant date | Jan 30, 2024 |
| Priority date | — |
| Expiry date | Mar 24, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Antibody heavy chain variable domains that can be paired with antibody light chain variable domains to form an antigen-binding site targeting the NKG2D receptor on natural killer cells are described. Proteins comprising an NKG2D antigen-binding site, pharmaceutical compositions and therapeutic methods thereof, including for the treatment of cancer, are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.