Method for inducing trans-differentiation of cardiomyocytes based on exosome
US11884935B2 · kind B2 · utility
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Key dates
| Filing date | Jun 28, 2019 |
| Grant date | Jan 30, 2024 |
| Priority date | — |
| Expiry date | Oct 23, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2506/1307
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a method for inducing trans-differentiation of cardiomyocytes based on exosome, and more particularly, to a method for inducing trans-differentiation of a fibroblast into a cardiomyocyte, comprising the steps of: isolating exosomes in a culture medium during a process of differentiating a stem cell into the cardiomyocyte; culturing a fibroblast in a cardiomyocyte reprogramming medium containing the isolated exosomes; and culturing the fibroblast cultured in a cardiomyocyte differentiation medium containing the isolated exosomes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.