Tissue-specific methylation marker
US11884966B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Mar 15, 2019 |
| Grant date | Jan 30, 2024 |
| Priority date | — |
| Expiry date | Nov 30, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/172
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are compositions comprising tissue-specific markers for identifying a tissue of origin of a cell-free nucleic acid, e.g., a cell-free DNA molecule. Also provided herein are methods, compositions, and systems for identifying a tissue of origin of a cell-free nucleic acid by determining an absolute amount of cell-free nucleic acids comprising the tissue-specific marker. Also provided herein are methods, compositions, and systems for detecting a cancer in a tissue of an organism by analyzing tissue-specific markers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.