Sequencing methods and compositions for prenatal diagnoses
US11884975B2 · kind B2 · utility
0Cited by
23References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 5, 2021 |
| Grant date | Jan 30, 2024 |
| Priority date | — |
| Expiry date | Mar 7, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/112
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods for determining aneuploidy and/or fetal fraction in maternal samples comprising fetal and maternal cfDNA by massively parallel sequencing. The method comprises a novel protocol for preparing sequencing libraries that unexpectedly improves the quality of library DNA while expediting the process of analysis of samples for prenatal diagnoses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.