Lattice light sheet microscope and method for tiling lattice light sheet in lattice light sheet microscope
US11885947B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 23, 2019 |
| Grant date | Jan 30, 2024 |
| Priority date | — |
| Expiry date | Sep 18, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B21/367
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A lattice light sheet microscope includes a single spatial light modulator (SLM), the optical modulation plane of which conjugates to an image plane of an excitation objective and which is configured to: generate an optical lattice by loading a phase map obtained from a central cross section of a corresponding optical lattice of a desired lattice light sheet, and tile the optical lattice by loading a phase map obtained from an off-center cross section of the corresponding optical lattice. The lattice light sheet microscope also includes a transparent annular diaphragm arranged at a plane conjugating to the entrance pupil of the excitation objective lens. The lattice light sheet microscope further includes a first galvanometer configured to: scan each optical lattice in the extending direction thereof so as to form a tiled lattice light sheet.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.