Patent · US Active

Combination therapies

US11890285B2 · kind B2 · utility

2Cited by
5References
43Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 23, 2020
Grant dateFeb 6, 2024
Priority date
Expiry dateAug 16, 2041

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K2039/505
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to combination therapies for treating KRas G12C cancers. In particular, the present invention relates to methods of treating cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a combination of a an agent that blocks Programmed Death-1 receptor (PD-1) and Programmed Death Ligand-1 (PD-L1) signaling and a KRAS G12C inhibitor of Formula (I), Formula I-A or Formula I-B, kits comprising the compositions and methods of use therefor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.