Patent · US Active

Inhibitors of cancer invasion, attachment, and/or metastasis

US11891399B2 · kind B2 · utility

0Cited by

2References

25Claims

0Family size

Assignees

Inventors

Paul Fisher · Scarsdale, US
Maurizio Pellecchia · San Diego, US
Swadesh K. Das · Richmond, US
Timothy P. Kegelman · Richmond, US
Bainan Wu · Richmond, US
Surya Kanta De · San Diego, US
Jun Wei · Village of La Jolla, US
Mitchell E. Menezes · Richmond, US
Luni Emdad · Richmond, US

Key dates

Filing date	Jan 14, 2021
Grant date	Feb 6, 2024
Priority date	—
Expiry date	Apr 20, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D495/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided herein are, inter alia, compositions that bind to a PDZ1 domain of MDA-9/Syntenin (syndecan binding protein: SDCBP), thereby inhibiting MDA-9/Syntenin activity, and methods of use of same. The compositions and methods provided herein are useful for treating cancer and preventing cancer metastasis, particularly in cancers that have increased MDA-9/Syntenin expression.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.