Fusion protein binding to CD47 protein and application thereof
US11891423B2 · kind B2 · utility
1Cited by
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9Claims
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Key dates
| Filing date | Apr 16, 2019 |
| Grant date | Feb 6, 2024 |
| Priority date | — |
| Expiry date | May 27, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided by the present invention are a fusion protein binding to a CD47 protein and an application thereof, wherein the fusion protein is capable of binding to a CD47 protein by using a KD value of 1×10−8M or lower. The fusion protein may specifically block the interaction between a CD47 protein and SIRPα without causing a blood coagulation reaction, and may further inhibit the growth and/or proliferation of tumors or tumor cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.