Patent · US Active

Anti-B7-H3 antibody and use thereof

US11891445B1 · kind B1 · utility

1Cited by
28References
14Claims
0Family size

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Inventors

Key dates

Filing dateMay 24, 2019
Grant dateFeb 6, 2024
Priority date
Expiry dateApr 14, 2040

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/70532
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided is an anti-B7-H3 antibody specifically recognizing a B7-H3, which can be usefully as a cancer therapeutic agent, as having an inhibitory activity of an immune checkpoint which induces antibody-dependent cell-mediated cytotoxicity and T cell activation inhibited by B7-H3. In particular, the antibody having the inhibitory activity of an immune checkpoint can be used in combination with other immunoantibody therapeutic agents. In addition, it can be usefully used for cancer targeting treatment including detection of various cancers expressing B7-H3 through specific binding to B7-H3, and drug delivery to specific cancer, etc.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.