Patent · US Active

RPE cell populations and methods of generating same

US11891622B2 · kind B2 · utility

0Cited by

33References

17Claims

0Family size

Assignee

CELL CURE NEUROSCIENCES LTD. · IL

Inventors

Osnat Bohana-Kashtan · Tel Mond, IL
Lior Ann Rosenberg Belmaker · Shoham, IL
Ofer Wiser · Jerusalem, IL

Key dates

Filing date	Dec 30, 2015
Grant date	Feb 6, 2024
Priority date	—
Expiry date	Dec 30, 2035

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2533/52
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A population of human polygonal RPE cells is disclosed. At least 95% of the cells thereof co-express premelanosome protein (PMEL17) and cellular retinaldehyde binding protein (CRALBP), wherein the trans-epithelial electrical resistance of the cells is greater than 100 ohms. Methods of generating same are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.