Tumor characterization and outcome prediction through quantitative measurements of tumor-associated vasculature

US11896349B2 · kind B2 · utility

Assignees

• CASE WESTERN RESERVE UNIVERSITY · US
• The United States Government as Represented by The Department of Veteran Affairs · US

Inventors

• Anant Madabhushi · Beachwood, US
• Nathaniel Braman · Cleveland, US

Key dates

• Filing date: Dec 9, 2020
• Grant date: Feb 13, 2024
• Expiry date: Sep 27, 2041

Classification

• Technology area (CPC G): Physics
• CPC primary: G06T2207/30101
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Embodiments discussed herein facilitate determination of a response to treatment and/or a prognosis for a tumor based at least in part on features of tumor-associated vasculature (TAV). One example embodiment is a method, comprising: accessing a medical imaging scan of a tumor, wherein the tumor is segmented on the medical imaging scan; segmenting tumor-associated vasculature (TAV) associated with the tumor based on the medical imaging scan; extracting one or more features from the TAV; providing the one or more features extracted from the TAV to a trained machine learning model; and receiving, from the machine learning model, one of a predicted response to a treatment for the tumor or a prognosis for the tumor.