Transdermal formulation for delivery of hydrophobic compounds and process for the preparation thereof
US11896575B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 16, 2018 |
| Grant date | Feb 13, 2024 |
| Priority date | — |
| Expiry date | May 26, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/46
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application includes a transdermal base formulation useful for example, for the transdermal delivery of active pharmaceutical ingredients along with a process for preparation thereof. In particular, the transdermal base formulation comprises: (a) an aqueous phase comprising water and at least one emulsion stabilizer; (b) an oil phase comprising at least one emulsifier, at least one emulsion stabilizer, at least one emollient comprising at least one flavonoid, at least one other emollient, and a terpene-rich natural butter; (c) an external phase comprising at least one terpene-rich extract or oil, at least one penetration enhancer and a phospholipid-complexed flavonoid; and optionally (d) at least one preservative phase.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.