Influenza virus vaccine and method of making
US11896661B2 · kind B2 · utility
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Key dates
| Filing date | Apr 27, 2018 |
| Grant date | Feb 13, 2024 |
| Priority date | — |
| Expiry date | Feb 6, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16134
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition for increasing vaccine yields due to increased virus growth in mutation comprising a vaccine strain bearing the Y161F mutation in hemagglutinin (HA). Y161F in HA increases HA thermostability without changing its original antigenic properties and enhances its binding affinity in the vaccine production platforms used in influenza vaccine manufacturing. A method for optimizing preparation of influenza vaccine seed strains which can further lower the cost of vaccines and increase profits for the vaccine companies, and also maintain antigenic stability during vaccine deliveries.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.