Targeted nucleic acid conjugate compositions
US11896672B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Apr 11, 2017 |
| Grant date | Feb 13, 2024 |
| Priority date | — |
| Expiry date | Apr 11, 2037 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides conjugates that comprise a targeting moiety, a nucleic acid, and optional linking groups as well as synthetic intermediates and synthetic methods useful for preparing the conjugates. The conjugates are useful to target therapeutic nucleic acids to the liver and to treat liver diseases including hepatitis (e.g. hepatitis B and hepatitis D).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.