Bioreactor and method of forming complex three-dimensional tissue constructs
US11898132B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 20, 2021 |
| Grant date | Feb 13, 2024 |
| Priority date | — |
| Expiry date | Jan 5, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2240/001
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A bioreactor and method of forming complex three-dimensional tissue constructs in a single culture chamber. The bioreactor and methods may be used to form multi-phasic tissue constructs having tissue formed from multiple cell types in a single culture chamber. The bioreactor includes at least one translation mechanism to facilitate translation of one or more tissue constructs without direct user intervention, thereby providing a closed, sterile environment for complex tissue fabrication. The bioreactor may be used as a stand-alone device or as part of a large-scale system including many bioreactors. The large-scale system may include a perfusion system to monitor and regulate the tissue culture environment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.