Ex vivo organ care system

US11903381B2 · kind B2 · utility

Assignee

• TRANSMEDICS, INC. · US

Inventors

• Waleed H. HASSANEIN · North Andover, US
• Tamer I. KHAYAL · North Andover, US
• Ahmed Elbetanony · North Andover, US
• Jeff Barnes · Medford, US
• Greg RITCHIE · Rowley, US
• Richard Bringham · North Andover, US
• Mark Anderson · Danvers, US
• John Sullivan · Land O' Lakes, US

Key dates

• Filing date: Apr 18, 2022
• Grant date: Feb 20, 2024
• Expiry date: Apr 18, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12M29/10
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The disclosure generally relates to a system for perfusing an ex-vivo liver including a pump configured to pump a perfusion fluid through a perfusion circuit, the pump in fluid communication with a hepatic artery interface and a portal vein interface; an oxygenator; a heater; an inferior vena cava interface in fluid communication with an inferior vena cava of the ex-vivo liver; and a reservoir configured to receive the perfusion fluid from the inferior vena cava of the ex-vivo liver and store a volume of fluid.