Cryopreservation method and apparatus
US11903383B2 · kind B2 · utility
0Cited by
7References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 12, 2018 |
| Grant date | Feb 20, 2024 |
| Priority date | — |
| Expiry date | Oct 18, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01N1/165
- WIPO fieldBasic materials chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to methods and apparatus for the cryopreservation of biological samples involving a density assisted vitrification wherein a sample of biological material in a cryopreservation agent is cooled from its top surface, causing an ice layer to form thereon. As cooling continues the ice layer grows downwards through the sample to provide a cryoprotectant and biological material rich layer below the ice layer that undergoes vitrification as cooling continues to below the glass transition temperature.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.