Diazabicyclooctanones as inhibitors of serine beta-lactamases
US11905286B2 · kind B2 · utility
1Cited by
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35Claims
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Key dates
| Filing date | Aug 8, 2019 |
| Grant date | Feb 20, 2024 |
| Priority date | — |
| Expiry date | Oct 2, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a compound which is a diazabicyclooctanone of Formula (I) or a pharmaceutically acceptable salt thereof: wherein R is as defined herein. The compounds are useful in the treatment of bacterial infection, in particular they are useful in reducing bacterial resistance to antibiotics. They are also useful in the treatment of bacteria which express serine-β-lactamase enzymes, in combination with antibiotics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.